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Early studies found no significant effect of intravenous GIP on bone resorption, 10 whereas more recently, GIP infusion was shown to suppress the bone resorption marker CTX-I and transiently increase the bone formation marker P1NP in people with T1D as well as healthy controls

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“It is of utmost importance to tailor treatment based on a patient’s genes, environment and previous medication use, to improve overall outcomes, decrease patients’ exposure to a drug that might not be effective and be considerate of the financial burden that patients may endure,” the researchers wrote.